Fasting for 24 hours may cut your risk of developing heart disease and diabetes.

LONDON: It seems your grandmother was right  fasting for a day is good for your health. And, now a study says that going without food for 24 hours may cut your risk of developing heart disease and diabetes.

Researchers have based their findings on an analysis of health and habits of over 200 residents in Utah. X-ray scans revealed narrowing of arteries in 75% of those who didn't fast. Clogged arteries affected 63% of those who said they often skipped meals.

Decrease in protein levels in kids a sign that the child will develop diabetes.

A study has found that the decreasing blood levels of a protein that helps control inflammation could be a sign that a child will develop diabetes.

Georgia Health Sciences University researchers are looking at blood levels of interleukin-1 receptor antagonist, or IL-1ra, in children because their genes put them at risk for type 1 diabetes.

They are also looking at diabetic mice missing IL-1ra to see how the protein deficiency affects immune function and destruction of insulin-producing islet beta cells.

“We want to know if we can use IL-1ra levels to identify children who will soon develop the disease, then use IL-1 inhibitors to prevent it,” Dr. Sharad Purohit, biochemist in the GHSU Center for Biotechnology and Genomic Medicine, said.

IL-1ra helps reduce inflammation and Purohit’s preliminary evidence suggests that low levels predict inflammation is increasing and the immune system is going to attack insulin-producing cells. 

Il-1 inhibitors already are used to treat rheumatoid arthritis, where inflammation destroys joints. Clinical trials are underway in type 1 diabetes and to see if an inhibitor can halt the islet cell destruction that occurs in type 1 diabetes as well.

Dr. Jin-Xiong She, Director of the Center for Biotechnology and Genomic Medicine said while acknowledging the inhibitor may improve type 1diabetes outcome, GHSU scientists want to know if it can also be used preventively.

IL-1ra competes with its counterpart IL-1beta for the IL-1 receptor. In type 1 diabetes, inflammation-promoting IL-1beta appears to be winning.

“It’s a balance; it’s a competition. There is always a balance between beta cell production and destruction and any process that can change the balance can push you to disease or help you recover from it,” she said. 

“In this case, we believe that knowing the balance is off can actually help prevent disease,” she added.

Diet fizzy drinks and other artificially sweetened beverages do not cause diabetes

A study has found that diet fizzy drinks and other artificially sweetened beverages do not cause diabetes, as had previously been thought.

Researchers at Harvard University said that while regular soda and other sugary drinks can increase a person's risk of diabetes, drinking artificially sweetened soft drinks, coffee or tea will not.

The levels of five amino acids in the blood could predict diabetes risk 10 yrs before first symptoms appear.

LONDON: Researchers from the Massachusetts General Hospital
(MGH) have suggested that measuring the levels of small molecules in
the blood could predict diabetes risk as much as a decade before first
symptoms appear.

They said the levels of five amino acids not
only indicated increased diabetes risk in a general population but also
could differentiate, among individuals with traditional risk factors
such as obesity, those most likely to actually develop diabetes.



"These findings raise the possibility that, in selected individuals,
these measurements could identify those at highest risk of developing
diabetes so that early preventive measures could be instituted," said
lead author Thomas Wang.

The researchers found that elevations in
five amino acids — isoleucine, leucine, valine, tyrosine and
phenylalanine — were significantly associated with the later development
of type 2 diabetes.



src:TOI

Diabetes Complications and causes of diabetes and steps to avoid diabetes

Complications related to diabetes can include heart and kidney disease, nerve damage, blindness and circulatory problems that can lead to wounds that will not heal and limb amputations.



Sadly, 1/3 of diabetics are undiagnosed and have no idea they are going to have liver failure or kidney failure or go blind or die thinking they have the flu or all four!
 

The way conventional medicine treat diabetes isn’t treating diabetes and prolonging it. diabetes can be reversed if a person wants to do it! Diabetes isn’t a sugar problem but malnutrition of the body’s organs.



Two causes of diabetes are;



#1 - When the liver becomes overwhelmed with toxins, such as toxic colors, toxic preservatives, chemicals from prescription and or over-the-counter drugs it can no longer support the pancreas and therefore the pancreas shuts down and needs cleansing.



#2 – The body becomes so full of fat that it smothers all the organs then the pancreas fails again.



Here are a few facts to keep you from becoming one of those diabetic statistics!



1. Watch your diet. Eat as much whole foods as possible

every day! Do not indulge in fast or prepackaged prepared

foods! Of course I know you are not going to do that as

fast foods or prepackaged prepared foods are too easy,

at least limit them to once or twice a month.



2. Keep your minerals balanced to help  every organ in your body function correctly while keeping a healthy

weight. If the whole world would get into the balanced minerals supplement daily there obesity and overweight people would be rare rather than 60% that exists now. Being overweight by more than 20 pounds sets you up for Diabetes.



3. Keep your Immune System Healthy! Just about

everyone ignores 75% to 80% of their immune system

because they have no idea where it is or what to do about

keeping it healthy. Where is it?
The  digestive Tract!



4. Do a liver and pancreas cleanse as often as needed!

Those living with toxic air, bathing or drinking or

cooking with chlorinated water and/or use toxic skin

care products need to do liver and pancreas cleanse

at least twice a year and every three months would be

best. For the person who eats a lot of prepackaged or

canned foods need three times a year minimum.



5. Eat organic foods as much as possible as they are

free of pesticides, fertilizer and GMO’s, this will limit

a toxic liver. Those chemicals build up in the body and

create all kinds of illness and disease in otherwise

healthy people.



6. Drink, bath and cook with pure filtered/purified

water! Our water systems are poison to us. Read

about the  waterways
dangers!



7. Stay away from prescription drugs or over-the-

counter drugs. Every manmade drug (NSAIDS,

prescription of every kind) has a warning “liver

must be check periodically” or words to that effect,

on every single manmade drug! Fact; drug-induced

liver injury is the most common reason for the

withdrawal from the market of an already FDA

approved drug.



8. Exercise, exercise, exercise! That doesn't mean

you need to pay for a gym membership! A simple brisk

walk works!



The above is for those who have not been diagnosed

as a diabetic but if you are already a diabetic try

natural alternative treating to become diabetic free! Read

about one of our most severe cases

diabetic-free for a few years now. And now

that you can be just like Richard!



Be smart with your health!

Controlling Diabetes With Lifestyle Changes

A diabetic is a person whose body is unable to produce adequate

and healthy amounts of insulin in order to control blood-sugar

levels. There are many different approaches designed to help

diabetics controlling diabetes, ranging from changing eating

habits to increasing physical activity.

Medication has also been shown to be an effective way of

controlling diabetes. Medical treatments for diabetes include

daily insulin injections, as well as taking insulin in the form

of a pill. The best approach though, appears to be a combination

of several factors.

Diabetes and being overweight almost go hand-in-hand. Most of

the time, individuals who are overweight have an increased risk

of becoming diabetic. For these individuals, most of their

problems result from an inactive, sedentary lifestyle, which is

consequently another contributing factor in the development of

diabetes.

Thin and active individuals should be aware that they too are

at risk for developing diabetes. In these cases, diabetes can

develop as much from genetics as it can from an unhealthy

lifestyle.

One major contributor to diabetes today is the fact that most

of today's foods are high in fat, and readily available. Today's

busy world make it difficult for individuals on-the-go to

prepare their own healthy meals, and as a result, they have no

other choice but to turn to fast food. Couple this with the fact

that many people today fail to get a daily amount exercise and

you literally have a recipe for disaster. Poor diet and poor

exercise are major contributors to the development of diabetes.

Avoiding exercise, eating lots of fatty foods and sugar within

your diet, as well as being overweight, are some of the major

contributing factors associated with diabetes.

The first step in fending off, or controlling diabetes is a

change in physical lifestyle. All people, especially diabetics

and those who are more at risk for developing diabetes, should

consider daily exercise. This exercise does not have to be

anything major. A thirty-minute a day walk, or even a short

weightlifting session at the gym can both be good places to

start.

Besides increasing the amount of daily activity, diabetics also

need to consider changing the way they eat. Everyone knows that

fast food tastes great, but for the diabetic, it might not be

the best choice. Instead of typical food choices, consider

something with a few less calories, and avoid foods that are

described as creamy, sautéed, or fried. More than likely, these

are the highest-calorie foods on the menu.

Diabetics should also avoid foods that contain high-fat and

high-calorie condiments like mayonnaise, butter, and cheese, as

well as certain high-carbohydrate sauces.

Diabetics should focus on eating foods that are low in

saturated fats and cholesterol. Most restaurants have skinless

chicken and fresh vegetables readily available on their menus.

Although there is no official or standard diabetic diet, there

are some standard lifestyle choices that diabetics can make to

ensure a healthy life. Most of the time, success comes down to a

willingness to achieve change.

About The Author: All about Diabetic Cooking- to keep You

Healthy And Happy! http://DiabeticCook ingSecrets. com Get your

Free e-book on GI (Glycemic Index)- See how easily you can use

GI as your guide to live healthier.

http://www.diabetic cookingsecrets.com/glycemic-index-spb.html

Wonder Healing Foods: Hot Cocoa for high BP, Cinnamon for diabetes, broccoli for ulcer and lots more...

Could hot cocoa be the next "wonder drug"

for high blood pressure?

Harvard researchers praise stunningly simple discovery!

According to recent estimates, nearly 1-in-3 American adults have high blood pressure. But for the Kuna Indians living on a group of islands off the Caribbean coast of Panama , hypertension doesn't even exist. In fact, after age 60, the average blood pressure for Kuna Indian islanders is a perfect 110/70. http://hallosushant.blogspot.com/

Is it because they eat less salt? No. Kuna Indians eat as much, if not more salt, than people in the U.S. Is it due to their genes? No. Kuna Indians who move away from the islands are just as likely to suffer from high blood pressure as anyone else! So what makes these folks practically "immune" to hypertension -- and lets them enjoy much lower death rates from heart attacks, strokes, diabetes, and cancer?

Harvard researchers were stunned to discover it's because they drink about 5 cups of cocoa each day. That's right, cocoa! Studies show the flavonols in cocoa stimulate your body's production of nitric oxide --boosting blood flow to your heart, brain, and other organs. In fact, one study found cocoa thins your blood just as well as low-dose aspirin!

http://hallosushant.blogspot.com/

But that's not all. A Harvard Medical School professor claims cocoa can also treat blocked arteries, congestive heart failure, stroke, dementia, even impotence!

Painless cholesterol cure

works in just 7 days -- and drives

the "food police" crazy!

Want to lower your cholesterol so fast it'll make your head spin? It's a breeze, just eat guacamole -- or any dish containing avocados!

Most health experts and nutritionists will tell you this rich, delicious Mexican dish is BANNED from any cholesterol-watcher's menu. But not Dr. Steven Pratt. That's because new research shows eating avocados can lower your cholesterol even faster than drugs... without the side effects! http://hallosushant.blogspot.com/

One study found after just 7 days on a diet including avocados, LDL ("bad") cholesterol and triglyceride levels dropped by 22 percent. Meanwhile, HDL ("good") cholesterol shot up 11 percent -- something most cholesterol-lowering drugs won't do!

The cinnamon cure for high blood sugar

Sprinkle a little cinnamon on your toast, cereal, oatmeal, or sliced apples. It not only tastes good, it lowers your blood sugar! In a recent study, people reduced their blood sugar levels by as much as 29 percent in just 40 days. That's with NO drugs, NO diet changes -- just plain old cinnamon!

The fat that blasts away cancer

You've been told cancer runs in families. You've been told what to eat and what NOT to eat -- including LESS fat.

http://hallosushant.blogspot.com/

Yet Dr. Steven Pratt says there's onefat you should eat MORE of. It's the monounsaturated fat called oleic acid, found in olive oil!

It should come as no surprise. After all, olive oil is a staple of the Mediterranean diet. And people in Spain and Greece are far less likely to develop cancer than in the U.S.

But what's really interesting is how olive oil not only prevents cancer, it blasts away cancer cells that already exist! So if you're even the slightest bit worried about cancer, this is one SuperFood you don't want to be without!

NEW prostate-protecting champ trumps tomatoes!

Unless you've been asleep under a rock for the past decade, you've heard the news about tomatoes. They contain a potent antioxidant calledlycopene that's been proven to reduce the risk of certain cancers -- in particular, prostate cancer.

A famous Harvard study back in 1995 found that out of 48,000 men surveyed, those who ate 10 or more servings of tomatoes a week reduced their risk of prostate cancer by more than one-third. What's more, they lowered their risk of aggressive prostate tumors (the kind that are really tough to treat) by HALF!

But before you reach for that slice of pizza or bottle of ketchup, listen up. What if I told you about a sweet, refreshing food Dr. Steven Pratt recommends that's even betterfor your prostate than tomatoes?

This NEW prostate protecting champ is watermelon! Ounce for ounce, watermelon is even richer in lycopene than tomatoes. And since you probably eat more watermelon in one sitting than you do tomatoes, you don't have to gorge on it 10 times a week in order to slash your cancer risk! Just a few times a week should do it.

Knock out an ulcer with broccoli?

About 25 million Americans will suffer from a peptic ulcer at some point in their lives. To get rid of their ulcers, most will take an antibiotic like amoxicillin. http://hallosushant.blogspot.com/

Pretty tame stuff, right? Wrong! Amoxicillin can bring with it unwanted side effects like fever, nausea, stomach pain, diarrhea, headache, even a yucky condition called "hairy tongue"!

And if you think that's bad, according to the Centers for Disease Control (CDC), the cost of treating an ulcer with antibiotics over an average 17-day period can run upward of $1,000!

Fortunately, there's one unconventional treatment with NO side effects Dr. Pratt swears by. "Eat broccoli!" he says. Why? Broccoli contains a remarkably potent compound called sulforaphane, which kills off the H. pylori bacteria that cause most ulcers. Not only can it knock out an ulcer, eating one serving a day for a month might run you 20 bucks... a fraction of the cost of drugs!

Kalmegh [A herbal medicine ] :An Antimicrobial, fights cancer,common cold, sinusitis, and tonsillitis also Diabetes

Since ancient times kalmegh, is used as a wonder drug in traditional Siddha and Ayurvedic systems of medicine. The therapeutic value of Kalmegh is due to its mechanism of action which is perhaps by enzyme induction. The plant extract exhibits antityphoid and antifungal activities. Kalmegh is also reported to possess antihepatotoxic, antibiotic, antimalarial, antihepatitic, antithrombogenic, antiinflammatory, antisnakevenom, and antipyretic properties to mention a few, besides its general use as an immunostimulant agent. A recent study conducted at Bastyr University, confirms anti-HIV activity of andrographolide.

The Flower

Andrographis

Scientific Name(s): Andrographis paniculata (Burm.f.) Wall. Nees. Family: Acanthaceae

Common Name(s): Kalmegh (Hindi), Kalmegha (Snaskrit), Chuanxinlian (Chinese), Kalupnath , Kirayat (Hindi), Mahatita (King of Bitters), Alui , Bhunimba , Bhui-neem , Yavatikta (Sanskrit), Sam biloto (Malay)

Famili : Acanthaceae

Location found : Widely distributed throughout the plains of India from uttar Pradesh to Assam, Madhya Pradesh, Tamil Nadu and Kerala.

A Ebook On Cultivation Of Kalmegh

kalmegh

The Plant

Clinical Overview

Uses of Andrographis

Kalmegh has been used for liver complaints and fever, and as an anti-inflammatory and immunostimulant. In clinical trials, Andrographis extract has been studied for use as an immunostimulant in upper respiratory tract infections and HIV infection. http://hallosushant.blogspot.com

The potential of andrographolide as an anticancer agent is being investigated. However, clinical evidence to support the use of Kalmegh for any indication is lacking.

Andrographis Dosing

The usual daily dose of andrographolides for common cold, sinusitis, and tonsillitis is 60 mg. Doses of 10 mg/kg resulted in the discontinuation of a clinical trial because of adverse reactions. Clinical trials in children with upper respiratory tract infection reported the use of andrographolide 30 mg daily for 10 days.http://hallosushant.blogspot.com

Dried Kalmegh

Andrographis Adverse Reactions

Headache, fatigue, rash, bitter/metallic taste, diarrhea, pruritus, and decreased sex drive were reported in 1 clinical trial. One HIV-positive participant experienced an anaphylactic reaction. Doses used in this trial were 10 mg/kg body weight.

Botany

A. paniculata is an erect annual herb that grows 30 to 110 cm in height and is native to India, China, and Southeast Asia. It is widely cultivated in Asia. The square stem has wings on the angles of new growth and is enlarged at the nodes, while small white flowers with rose-purple spots are borne on a spreading panicle. The plant produces yellowish-brown seeds, and all parts have an extremely bitter taste. The portion of the plant appearing above ground are harvested in the fall. The genetic variability of the species has been examined.http://hallosushant.blogspot.com

History

A. paniculata has been used for centuries in India, China, Thailand, and other Asian countries and is present in 26 different polyherbal formulations in the Ayurvedic traditional health system. Kalmegh is listed in the 1992 Pharmacopoeia of the Peoples Republic of China as a cold property herb used to rid the body of fevers and dispel toxins. An immunostimulant preparation known as Kan Jang , which contains Kalmegh and eleutherococcushas, been used in Scandinavian countries for 20 years. Kalmegh is also manufactured and marketed in the United States.

Chemistry

The diterpene lactone andrographolide was first isolated as a major constituent 6 and later characterized as a lactone.  Its full structure was determined in the 1960s,  and x-ray crystallography later confirmed the structure.  A number of related minor diterpenes and their glycosides have since been identified.Methods of analysis, including high-pressure liquid chromatography and nuclear magnetic resonance,  have been published. A method for rapid isolation of andrographolide is also available.  When callus cultures of the plant were investigated, andrographolide and the other diterpenes were not produced. Instead, the sesquiterpenes paniculides A-C were found.  Other constituents of the plant include various flavones.  http://hallosushant.blogspot.com

Andrographis Uses and Pharmacology

Antimicrobial

Extracts of Andrographis and andrographolide derivatives have shown modest activity in vitro against HIV ; however, a phase 1 study of andrographolide showed no effect on viral replication after 6 weeks, despite increased CD4 counts. http://hallosushant.blogspot.com

Activity in antimalarial screens has also been noted for Andrographis extracts, but clinical trials are lacking. http://hallosushant.blogspot.com

The extract of A. paniculata blocked Escherichia coli enterotoxin-induced secretion in rabbit and guinea pig models of diarrhea. Andrographolide and 3 other related diterpenes were responsible for this action.  Other in vitro experiments present conflicting results for the action of andrographolide and leaf extracts on E. coli . http://hallosushant.blogspot.comhttp://hallosushant.blogspot.com

Cancer

Animal and in vitro experiments using human cancer cell lines to investigate the potential anticancer effects of A.

paniculata have found andrographolide responsible for the observed effects rather than other diterpenes.  Various mechanisms of action have been proposed, including enhancement of chemokine activity, inhibition of tumor-specific angiogenesis affecting cell cycle progression, and induction of apoptosis. Cancer cell lines investigated include prostate, breast, cervical, colon, hepatoma, melanoma, and lymphocytic leukemia. Researchers are now focusing on synthesizing compounds based on andrographolide to improve selectivity and potency. 

The need for caution has been raised by one group of researchers because andrographolide-enhanced SDF-1-chemokine activity might induce tumor cell metastasis. . paniculata extract has also induced cell differentiation in mouse myeloid leukemia cells. http://hallosushant.blogspot.com

Immunostimulant

Animal data

Both antigen-specific and antigen-nonspecific immune responses in mice were stimulated by andrographolide and an ethanolic extract; the extract was more potent than andrographolide, suggesting that other constituents also were immunostimulants. Inhibition of passive cutaneous anaphylaxis and mast cell stabilization was observed in studies of the purified diterpenes in rats. 

Clinical data

A systematic review of 4 clinical trials found A. paniculata , either alone or in a fixed combination with A. senticosus ( Kan Jang ), significantly more effective than placebo ( P < p =" 0.0002,">

A small study in patients with familial Mediterranean fever (Nߙ=ߙ24) found a decrease in frequency, duration, and severity of febrile attacks, compared with placebo. 

Stimulation of the production of key cytokines and immune activation markers has been investigated as potential mechanisms of andrographolide immunomodulation. http://hallosushant.blogspot.com

Other uses

Extracts of Andrographis have demonstrated hypoglycemic action in rats with streptozotocin- and alloxan-induced diabetes, supporting a traditional use of Kalmegh.  Clinical trials are lacking.

Two older trials explored a possible hypotensive effect of andrographolide/Kalmegh, but further investigation has not been conducted. 

Animal experiments suggest that the extract of A. paniculata is hepatoprotective, but clinical trials are lacking. Hepatic drug-metabolizing enzymes were elevated in 1 animal experiment,  however, in a clinical trial, elevated liver enzymes (AST and ALT) were reported. 

Andrographolide has demonstrated anti-inflammatory effects in several cellular systems, including prevention of phorbol ester-induced reactive oxygen species and N-formyl-methionyl-leucyl-phenylalanine-induced adhesion in rat neutrophils,  inhibition of tumor necrosis factor-induced upregulation of intercellular adhesion molecule expression, and monocyte adhesion 57 and activation of protein kinase pathways. 

Dosage

Kalmegh dosage in clinical studies has ranged from 3 to 6 g of the crude plant.

The usual daily dose of andrographolides for common cold, sinusitis, and tonsillitis is 60 mg, but doses up to 1,200 mg have been reported. Andrographolide 48 mg daily was used in a trial of familial Mediterranean fever. Doses of 5 to 10 mg/kg were used in a trial in HIV patients, but adverse reactions at this dosage stopped the trial. 

Clinical trials in children with upper respiratory tract infection reported the use of andrographolide 30 mg daily for 10 days. 

Adverse Reactions

Research reveals few adverse reactions reported with the use of A. paniculata . However, adverse reactions (eg, headache, fatigue, rash, bitter/metallic taste, diarrhea, pruritus, decreased sex drive) during a phase 1 study of andrographolide in HIV required interruption of the trial. One HIV-positive participant experienced an anaphylactic reaction. Doses of andrographolide 10 mg/kg body weight were used when the adverse reactions became apparent.  In the same trial, elevated liver enzymes were experienced by many of the participants. Two cases of urticaria have been reported in other trials.

Toxicology

Toxicology studies are limited, but Kalmegh does not appear to be acutely toxic. Acute lethal doses (median lethal dose) in mice are reported to be more than 40 g/kg for andrographolide.

Male reproductive toxicology of Andrographis has been studied. A subchronic 60-day study in male rats showed no changes in testicular weight, histology, or testosterone levels.  However, detailed studies in rats given purified andrographolide for 48 days showed decreases in sperm counts and motility that were linked to disruption of spermatogenesis. 

A small, short-duration, phase 1 clinical trial in healthy men found no negative effects at doses 3 times the usual daily dose of Kan Jang . Instead, a positive trend in the number of spermatozoids, percent active forms, and fertility indexes was found. Limitations of the study included the small number of participants (N = 14), the short duration of the study (10 days), and the low dose tested (3 times the normal dose versus 10-fold in animal studies).